About 5 results found for searched term "IDH1 Inhibitor 7" (0.135 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M54534 | IDH1 Inhibitor 7 | Isocitrate Dehydrogenase (IDH) |
| IDH1 Inhibitor 7 is an IDH1 inhibitor with an IC50 of less than 100 nM. | ||
| M10335 | IDH-305 | Isocitrate Dehydrogenase (IDH) |
| IDH305 | ||
| IDH-305 is an orally available, mutant-selective and brain-penetrant IDH1 inhibitor that targets IDH1(R132) mutation with IC50 values of 27 nM, 28 nM and 6.14 μM for IDH1R132H, IDH1R132C and IDH1WT, respectively. | ||
| M14456 | Mutant IDH1 inhibitor | Isocitrate Dehydrogenase (IDH) |
| Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of < 72 nM. | ||
| M42452 | IHMT-IDH1-053 | Isocitrate Dehydrogenase (IDH) |
| IHMT-IDH1-053 is a highly selectivity and irreversible IDH1-mutant inhibitor with an IC50 of 4.7 nM for IDH1 R132H. | ||
| M54537 | Mutant IDH1-IN-4 | Isocitrate Dehydrogenase (IDH) |
| Mutant IDH1-IN-4 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH 1) with an IC50 value of ≤ 0.5 μM for mutant IDH 1 in R132H, HT1080 and U87R132H cells. | ||
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